{"id":11230,"date":"2022-04-29T20:47:46","date_gmt":"2022-04-29T20:47:46","guid":{"rendered":"https:\/\/insilicall.com\/?p=11230"},"modified":"2023-02-16T20:16:54","modified_gmt":"2023-02-16T20:16:54","slug":"atualizacao-anvisa-controle-nitrosaminas","status":"publish","type":"post","link":"https:\/\/insilicall.com\/atualizacao-anvisa-controle-nitrosaminas\/","title":{"rendered":"Atualiza\u00e7\u00e3o da ANVISA: controle de nitrosaminas"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"11230\" class=\"elementor elementor-11230\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-694b653 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"694b653\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-dd0c2a4\" data-id=\"dd0c2a4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-588076b elementor-widget elementor-widget-heading\" data-id=\"588076b\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h2 class=\"elementor-heading-title elementor-size-large\">Atualiza\u00e7\u00e3o da ANVISA sobre o controle de nitrosaminas em medicamentos de uso humano<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c86fba elementor-widget elementor-widget-text-editor\" data-id=\"4c86fba\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>No dia 27 de Abril de 2022, mediante \u00e0 reuni\u00e3o extraordin\u00e1ria realizada pela ANVISA, o que antes era apenas uma recomenda\u00e7\u00e3o tornou-se oficialmente uma normativa, a RDC j\u00e1 foi publicada pelo Di\u00e1rio Oficial da Uni\u00e3o, sendo ela a <a href=\"https:\/\/www.in.gov.br\/en\/web\/dou\/-\/resolucao-rdc-n-677-de-28-de-abril-de-2022-397561756\" target=\"_blank\" rel=\"noopener nofollow\"><strong><span style=\"color: #003366\">RDC n\u00ba 677, de 28 de Abril de 2022<\/span>.<\/strong><\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-82f6ae4 elementor-widget elementor-widget-text-editor\" data-id=\"82f6ae4\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Para quem ainda n\u00e3o se ambientou, estamos falando sobre as recomenda\u00e7\u00f5es para avalia\u00e7\u00e3o de risco de nitrosaminas. Inicialmente foram investigadas nos medicamentos da classe das sartanas, entretanto, sua procura hoje se expande e abrange para todos os medicamentos <br \/>de uso humano.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3ac92f8 elementor-widget elementor-widget-text-editor\" data-id=\"3ac92f8\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u00a0<\/p><p><a href=\"https:\/\/insilicall.com\/n-nitrosaminas-e-toxicologia-regulatoria-anvisa\/\"><b><i>+ Leia sobre N<\/i><\/b><b><i>itrosaminas e sua implica\u00e7\u00e3o para sa\u00fade humana nessa mat\u00e9ria aqui.<\/i><\/b><\/a><\/p><p><a href=\"https:\/\/insilicall.com\/tag\/nitrosaminas\/\"><b><i>+ Mais sobre o universo das Nitrosaminas.<\/i><\/b><\/a><\/p><p>\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-c552af2 elementor-widget elementor-widget-text-editor\" data-id=\"c552af2\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Desde 2018, a ANVISA vem tomando medidas preventivas quanto \u00e0 disposi\u00e7\u00e3o de nitrosaminas, de forma que as farmac\u00eauticas possam atuar proativamente e com autonomia em seus portf\u00f3lios. As orienta\u00e7\u00f5es dispon\u00edveis no <\/span><span style=\"color: #003366\"><a style=\"color: #003366\" href=\"http:\/\/antigo.anvisa.gov.br\/documents\/10181\/6279847\/(1)Guia_50_Nitrosaminas_rev_final_para+publica%C3%A7%C3%A3o.pdf\/12af2904-e5a7-4774-9528-f4f633cac2bf\" target=\"_blank\" rel=\"noopener\"><b>Guia 50<\/b><\/a><\/span><span style=\"font-weight: 400\"> permanecem v\u00e1lidas, e servem de norte para todas as ind\u00fastrias.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a5c0477 elementor-widget elementor-widget-text-editor\" data-id=\"a5c0477\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Segundo o Guia, os medicamentos devem passar pelo fluxo avaliativo e prosseguir com as an\u00e1lises caso haja presen\u00e7a de nitrosaminas nos medicamentos ou poss\u00edvel forma\u00e7\u00e3o delas. <\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e1f8710 elementor-widget elementor-widget-text-editor\" data-id=\"e1f8710\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Etapa 1 &#8211; An\u00e1lise de risco<\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-22cf1d6 elementor-widget elementor-widget-text-editor\" data-id=\"22cf1d6\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>I<span style=\"font-weight: 400\">nvestiga\u00e7\u00e3o, identifica\u00e7\u00e3o e avalia\u00e7\u00e3o do risco oriundo da rota de s\u00edntese do IFA, do processo produtivo e do armazenamento do medicamento que possibilite a presen\u00e7a ou a forma\u00e7\u00e3o de nitrosaminas potencialmente carcinog\u00eanicas.<\/span><\/p><p><span style=\"font-weight: 400\">A investiga\u00e7\u00e3o por nitrosaminas deve contemplar:<\/span><\/p><ol><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Reagentes e demais materiais.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Recupera\u00e7\u00e3o de materiais.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Degrada\u00e7\u00e3o de materiais.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Contamina\u00e7\u00e3o cruzada entre processos.<\/span><\/li><li style=\"font-weight: 400\"><span style=\"font-weight: 400\">Processo produtivo, incluindo intera\u00e7\u00e3o te\u00f3rica entre IFA, excipiente e embalagem.<\/span><\/li><\/ol><p><span style=\"font-weight: 400\">Caso seja identificado risco de presen\u00e7a de nitrosaminas como resultado da Etapa 1, <br \/>a empresa deve prosseguir para a Etapa 2 e realizar os testes confirmat\u00f3rios.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2d2473b elementor-widget elementor-widget-text-editor\" data-id=\"2d2473b\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Etapa 2 &#8211; Testes Confirmat\u00f3rios<\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cd9e867 elementor-widget elementor-widget-text-editor\" data-id=\"cd9e867\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">A empresa dever\u00e1 utilizar m\u00e9todos anal\u00edticos adequadamente sens\u00edveis para a quantifica\u00e7\u00e3o dessas impurezas, a fim de admitir ou refutar a presen\u00e7a de nitrosaminas no IFA ou produto acabado. Seu in\u00edcio acontece imediatamente ap\u00f3s a conclus\u00e3o da avalia\u00e7\u00e3o de risco.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ca28594 elementor-widget elementor-widget-text-editor\" data-id=\"ca28594\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Etapa 3 &#8211; Controle de nitrosaminas para produtos regularizados<\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-79e4e26 elementor-widget elementor-widget-text-editor\" data-id=\"79e4e26\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Caso os resultados da Etapa 2 atestem a contamina\u00e7\u00e3o em n\u00edveis acima do aceit\u00e1vel, a empresa deve protocolar junto a ANVISA os documentos necess\u00e1rios para que uma medida possa ser tomada, como o recolhimento volunt\u00e1rio do medicamento. Da mesma forma, emitir relat\u00f3rios de mudan\u00e7as implementadas para prevenir ou reduzir impurezas de nitrosaminas em IFAs e produtos acabados.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-17d845d elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"17d845d\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3556e54\" data-id=\"3556e54\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-11a2fc0 elementor-widget elementor-widget-heading\" data-id=\"11a2fc0\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-large\">Principais mudan\u00e7as propostas na reuni\u00e3o<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f57ee5b elementor-widget elementor-widget-text-editor\" data-id=\"f57ee5b\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Logo na etapa de avalia\u00e7\u00e3o de riscos as empresas devem desenvolver uma matriz de risco que define a sequ\u00eancia de <\/span><b>avalia\u00e7\u00e3o dos produtos de todo seu portf\u00f3lio<\/b><span style=\"font-weight: 400\"> (de medicamentos para uso humano) contemplando as categorias de risco: <\/span><b><i>muito alto, alto, m\u00e9dio, baixo e muito baixo.<\/i><\/b><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4489fcb elementor-widget elementor-widget-text-editor\" data-id=\"4489fcb\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Por interm\u00e9dio dessa classifica\u00e7\u00e3o a empresa deve se atentar a cumprir os prazos estabelecidos para atender os requisitos de controle de nitrosaminas.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-982957d elementor-widget elementor-widget-text-editor\" data-id=\"982957d\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>1\u00ba de mar\u00e7o de 2023: <\/b><span style=\"font-weight: 400\">avalia\u00e7\u00e3o de risco para produtos classificados como risco <\/span><b>muito alto.<\/b><\/p><p><b>1\u00ba Junho de 2023:<\/b><span style=\"font-weight: 400\"> avalia\u00e7\u00e3o de risco para produtos classificados como risco <\/span><b>alto.<\/b><\/p><p><b>2 de Junho de 2025:<\/b><span style=\"font-weight: 400\"> avalia\u00e7\u00e3o de risco para os <\/span><b>demais produtos da empresa.<\/b><\/p><p><b>At\u00e9 36 meses<\/b><span style=\"font-weight: 400\"> a partir da conclus\u00e3o da avalia\u00e7\u00e3o de risco: in\u00edcio dos testes confirmat\u00f3rios e protocolos dos peticionamentos de altera\u00e7\u00f5es p\u00f3s-registro necess\u00e1rios. <\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-8bca188 elementor-widget elementor-widget-text-editor\" data-id=\"8bca188\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Ainda que sua divulga\u00e7\u00e3o j\u00e1 tenha acontecido, a RDC <strong>entra em vigor apenas no dia 1\u00ba de Junho de 2022<\/strong>, e a partir de ent\u00e3o as empresas ter\u00e3o menos de 1 ano para entrarem em acordo com a ANVISA em rela\u00e7\u00e3o aos medicamentos classificados como sendo de risco \u201cmuito alto\u201d.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-132ffc1 elementor-widget elementor-widget-text-editor\" data-id=\"132ffc1\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">O cumprimento da normativa garante a preven\u00e7\u00e3o de poss\u00edveis problemas futuros decorrentes das nitrosaminas. E al\u00e9m de manter seu produto dispon\u00edvel no mercado, com uma r\u00e1pida adequa\u00e7\u00e3o, \u00e9 garantido tratamento seguro a todos os consumidores.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-3da2f92 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3da2f92\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-708d506\" data-id=\"708d506\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3beb6db elementor-widget elementor-widget-heading\" data-id=\"3beb6db\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h2 class=\"elementor-heading-title elementor-size-large\">Uma perspectiva sobre o cen\u00e1rio regulat\u00f3rio a seguir<\/h2>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7fefc67 elementor-widget elementor-widget-text-editor\" data-id=\"7fefc67\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Dado o enorme volume de medicamentos a serem avaliados, \u00e9 l\u00f3gico pressupor a alta demanda e longas esperas pela avalia\u00e7\u00e3o de todo um portf\u00f3lio. As empresas de tecnologia, <br \/>j\u00e1 amplamente procuradas, s\u00e3o hoje aquelas que entregam resultados assertivos em menor tempo h\u00e1bil. \u00c9 prov\u00e1vel que elas sofram uma sobrecarga de servi\u00e7os, em prol de vencer todas as demandas, e quem leva a melhor \u00e9 sempre quem chega primeiro.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-119c8a6 elementor-widget elementor-widget-text-editor\" data-id=\"119c8a6\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">E a verdade \u00e9 que podemos observar certo padr\u00e3o de comportamento e a\u00e7\u00e3o, conforme <br \/>o tempo passa e o prazo vai se aproximando a urg\u00eancia e o frenesi aumentam. Afetando principalmente aqueles que protelam o in\u00edcio de suas avalia\u00e7\u00f5es, em decorr\u00eancia disso, podemos prever uma demanda crescente e um fluxo de avalia\u00e7\u00f5es bastante congestionado nos \u00faltimos meses de 2022 e in\u00edcio de 2023.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-38f1c25 elementor-widget elementor-widget-text-editor\" data-id=\"38f1c25\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Diversas estrat\u00e9gias podem ser utilizadas para que este quadro seja evitado, como a contrata\u00e7\u00e3o de uma ou mais empresas para dar in\u00edcio a avalia\u00e7\u00e3o de risco de nitrosaminas <br \/>e iniciar com anteced\u00eancia todo o processo.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5417a97 elementor-widget elementor-widget-text-editor\" data-id=\"5417a97\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Aqui na InsilicAll, dispomos de metodologias computacionais avan\u00e7adas e empregamos Intelig\u00eancia Artificial no fluxo de nitrosaminas. Os dados, ent\u00e3o, s\u00e3o submetidos \u00e0 nossa equipe multidisciplinar de especialistas, de forma que eles possam fazer a interpreta\u00e7\u00e3o e delibera\u00e7\u00f5es correspondentes. Dessa maneira, aliando cientistas e tecnologia, garantimos alta precis\u00e3o e rapidez em nossos resultados.\u00a0<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-23a369f elementor-widget elementor-widget-text-editor\" data-id=\"23a369f\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><em><a href=\"https:\/\/insilicall.com\/biologia-computacional-o-futuro-da-pd\/\"><b>+ Conhe\u00e7a um pouco mais sobre as metodologias computacionais neste artigo aqui<\/b><\/a><b>.<\/b><\/em><\/p><p><em><a href=\"https:\/\/insilicall.com\/fluxo-insilicall-qualificacao-nitrosaminas\/\"><b>+ Leia um pouco mais sobre o processo de qualifica\u00e7\u00e3o de nitrosaminas realizados.<\/b><\/a><\/em><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-e240b13 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"e240b13\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.23.0 - 05-08-2024 *\/\n.elementor-widget-divider{--divider-border-style:none;--divider-border-width:1px;--divider-color:#0c0d0e;--divider-icon-size:20px;--divider-element-spacing:10px;--divider-pattern-height:24px;--divider-pattern-size:20px;--divider-pattern-url:none;--divider-pattern-repeat:repeat-x}.elementor-widget-divider .elementor-divider{display:flex}.elementor-widget-divider .elementor-divider__text{font-size:15px;line-height:1;max-width:95%}.elementor-widget-divider .elementor-divider__element{margin:0 var(--divider-element-spacing);flex-shrink:0}.elementor-widget-divider .elementor-icon{font-size:var(--divider-icon-size)}.elementor-widget-divider .elementor-divider-separator{display:flex;margin:0;direction:ltr}.elementor-widget-divider--view-line_icon .elementor-divider-separator,.elementor-widget-divider--view-line_text .elementor-divider-separator{align-items:center}.elementor-widget-divider--view-line_icon .elementor-divider-separator:after,.elementor-widget-divider--view-line_icon .elementor-divider-separator:before,.elementor-widget-divider--view-line_text .elementor-divider-separator:after,.elementor-widget-divider--view-line_text .elementor-divider-separator:before{display:block;content:\"\";border-block-end:0;flex-grow:1;border-block-start:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--element-align-left .elementor-divider .elementor-divider-separator>.elementor-divider__svg:first-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-left .elementor-divider-separator:before{content:none}.elementor-widget-divider--element-align-left .elementor-divider__element{margin-left:0}.elementor-widget-divider--element-align-right .elementor-divider .elementor-divider-separator>.elementor-divider__svg:last-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-right .elementor-divider-separator:after{content:none}.elementor-widget-divider--element-align-right .elementor-divider__element{margin-right:0}.elementor-widget-divider--element-align-start .elementor-divider .elementor-divider-separator>.elementor-divider__svg:first-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-start .elementor-divider-separator:before{content:none}.elementor-widget-divider--element-align-start .elementor-divider__element{margin-inline-start:0}.elementor-widget-divider--element-align-end .elementor-divider .elementor-divider-separator>.elementor-divider__svg:last-of-type{flex-grow:0;flex-shrink:100}.elementor-widget-divider--element-align-end .elementor-divider-separator:after{content:none}.elementor-widget-divider--element-align-end .elementor-divider__element{margin-inline-end:0}.elementor-widget-divider:not(.elementor-widget-divider--view-line_text):not(.elementor-widget-divider--view-line_icon) .elementor-divider-separator{border-block-start:var(--divider-border-width) var(--divider-border-style) var(--divider-color)}.elementor-widget-divider--separator-type-pattern{--divider-border-style:none}.elementor-widget-divider--separator-type-pattern.elementor-widget-divider--view-line .elementor-divider-separator,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:after,.elementor-widget-divider--separator-type-pattern:not(.elementor-widget-divider--view-line) .elementor-divider-separator:before,.elementor-widget-divider--separator-type-pattern:not([class*=elementor-widget-divider--view]) .elementor-divider-separator{width:100%;min-height:var(--divider-pattern-height);-webkit-mask-size:var(--divider-pattern-size) 100%;mask-size:var(--divider-pattern-size) 100%;-webkit-mask-repeat:var(--divider-pattern-repeat);mask-repeat:var(--divider-pattern-repeat);background-color:var(--divider-color);-webkit-mask-image:var(--divider-pattern-url);mask-image:var(--divider-pattern-url)}.elementor-widget-divider--no-spacing{--divider-pattern-size:auto}.elementor-widget-divider--bg-round{--divider-pattern-repeat:round}.rtl .elementor-widget-divider .elementor-divider__text{direction:rtl}.e-con-inner>.elementor-widget-divider,.e-con>.elementor-widget-divider{width:var(--container-widget-width,100%);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 126 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M10.7,6l2.5,2.6l-4,4.3l4,5.4l-2.5,1.9l-4.5-5.2l-3.9,4.2L0.7,17L4,13.1L0,8.6l2.3-1.3l3.9,3.9L10.7,6z M23.9,6.6l4.2,4.5L32,7.2l2.3,1.3l-4,4.5l3.2,3.9L32,19.1l-3.9-3.3l-4.5,4.3l-2.5-1.9l4.4-5.1l-4.2-3.9L23.9,6.6zM73.5,6L76,8.6l-4,4.3l4,5.4l-2.5,1.9l-4.5-5.2l-3.9,4.2L63.5,17l4.1-4.7L63.5,8l2.3-1.3l4.1,3.6L73.5,6z M94,6l2.5,2.6l-4,4.3l4,5.4L94,20.1l-3.9-5l-3.9,4.2L84,17l3.2-3.9L84,8.6l2.3-1.3l3.2,3.9L94,6z M106.9,6l4.5,5.1l3.9-3.9l2.3,1.3l-4,4.5l3.2,3.9l-1.6,2.1l-3.9-4.2l-4.5,5.2l-2.5-1.9l4-5.4l-4-4.3L106.9,6z M53.1,6l2.5,2.6l-4,4.3l4,4.6l-2.5,1.9l-4.5-4.5l-3.5,4.5L43.1,17l3.2-3.9l-4-4.5l2.3-1.3l3.9,3.9L53.1,6z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a33d5b elementor-widget elementor-widget-text-editor\" data-id=\"3a33d5b\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Abaixo est\u00e1 dipon\u00edvel o PDF para conhecer mais informa\u00e7\u00f5es sobre fluxo <\/strong><strong>de <\/strong><strong>avalia\u00e7\u00e3o de nitrosaminas realizado pela InsilicAll, responda o formul\u00e1rio e receba o material diretamente <br>no seu email.<\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3c22fad elementor-button-align-stretch elementor-widget elementor-widget-form\" data-id=\"3c22fad\" data-element_type=\"widget\" data-settings=\"{&quot;step_next_label&quot;:&quot;Next&quot;,&quot;step_previous_label&quot;:&quot;Previous&quot;,&quot;step_type&quot;:&quot;number_text&quot;,&quot;step_icon_shape&quot;:&quot;circle&quot;,&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"form.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor-pro - v3.20.0 - 26-03-2024 *\/\n.elementor-button.elementor-hidden,.elementor-hidden{display:none}.e-form__step{width:100%}.e-form__step:not(.elementor-hidden){display:flex;flex-wrap:wrap}.e-form__buttons{flex-wrap:wrap}.e-form__buttons,.e-form__buttons__wrapper{display:flex}.e-form__indicators{display:flex;justify-content:space-between;align-items:center;flex-wrap:nowrap;font-size:13px;margin-bottom:var(--e-form-steps-indicators-spacing)}.e-form__indicators__indicator{display:flex;flex-direction:column;align-items:center;justify-content:center;flex-basis:0;padding:0 var(--e-form-steps-divider-gap)}.e-form__indicators__indicator__progress{width:100%;position:relative;background-color:var(--e-form-steps-indicator-progress-background-color);border-radius:var(--e-form-steps-indicator-progress-border-radius);overflow:hidden}.e-form__indicators__indicator__progress__meter{width:var(--e-form-steps-indicator-progress-meter-width,0);height:var(--e-form-steps-indicator-progress-height);line-height:var(--e-form-steps-indicator-progress-height);padding-right:15px;border-radius:var(--e-form-steps-indicator-progress-border-radius);background-color:var(--e-form-steps-indicator-progress-color);color:var(--e-form-steps-indicator-progress-meter-color);text-align:right;transition:width .1s linear}.e-form__indicators__indicator:first-child{padding-left:0}.e-form__indicators__indicator:last-child{padding-right:0}.e-form__indicators__indicator--state-inactive{color:var(--e-form-steps-indicator-inactive-primary-color,#c2cbd2)}.e-form__indicators__indicator--state-inactive [class*=indicator--shape-]:not(.e-form__indicators__indicator--shape-none){background-color:var(--e-form-steps-indicator-inactive-secondary-color,#fff)}.e-form__indicators__indicator--state-inactive object,.e-form__indicators__indicator--state-inactive svg{fill:var(--e-form-steps-indicator-inactive-primary-color,#c2cbd2)}.e-form__indicators__indicator--state-active{color:var(--e-form-steps-indicator-active-primary-color,#39b54a);border-color:var(--e-form-steps-indicator-active-secondary-color,#fff)}.e-form__indicators__indicator--state-active [class*=indicator--shape-]:not(.e-form__indicators__indicator--shape-none){background-color:var(--e-form-steps-indicator-active-secondary-color,#fff)}.e-form__indicators__indicator--state-active object,.e-form__indicators__indicator--state-active svg{fill:var(--e-form-steps-indicator-active-primary-color,#39b54a)}.e-form__indicators__indicator--state-completed{color:var(--e-form-steps-indicator-completed-secondary-color,#fff)}.e-form__indicators__indicator--state-completed [class*=indicator--shape-]:not(.e-form__indicators__indicator--shape-none){background-color:var(--e-form-steps-indicator-completed-primary-color,#39b54a)}.e-form__indicators__indicator--state-completed .e-form__indicators__indicator__label{color:var(--e-form-steps-indicator-completed-primary-color,#39b54a)}.e-form__indicators__indicator--state-completed .e-form__indicators__indicator--shape-none{color:var(--e-form-steps-indicator-completed-primary-color,#39b54a);background-color:initial}.e-form__indicators__indicator--state-completed object,.e-form__indicators__indicator--state-completed svg{fill:var(--e-form-steps-indicator-completed-secondary-color,#fff)}.e-form__indicators__indicator__icon{width:var(--e-form-steps-indicator-padding,30px);height:var(--e-form-steps-indicator-padding,30px);font-size:var(--e-form-steps-indicator-icon-size);border-width:1px;border-style:solid;display:flex;justify-content:center;align-items:center;overflow:hidden;margin-bottom:10px}.e-form__indicators__indicator__icon img,.e-form__indicators__indicator__icon object,.e-form__indicators__indicator__icon svg{width:var(--e-form-steps-indicator-icon-size);height:auto}.e-form__indicators__indicator__icon .e-font-icon-svg{height:1em}.e-form__indicators__indicator__number{width:var(--e-form-steps-indicator-padding,30px);height:var(--e-form-steps-indicator-padding,30px);border-width:1px;border-style:solid;display:flex;justify-content:center;align-items:center;margin-bottom:10px}.e-form__indicators__indicator--shape-circle{border-radius:50%}.e-form__indicators__indicator--shape-square{border-radius:0}.e-form__indicators__indicator--shape-rounded{border-radius:5px}.e-form__indicators__indicator--shape-none{border:0}.e-form__indicators__indicator__label{text-align:center}.e-form__indicators__indicator__separator{width:100%;height:var(--e-form-steps-divider-width);background-color:#babfc5}.e-form__indicators--type-icon,.e-form__indicators--type-icon_text,.e-form__indicators--type-number,.e-form__indicators--type-number_text{align-items:flex-start}.e-form__indicators--type-icon .e-form__indicators__indicator__separator,.e-form__indicators--type-icon_text .e-form__indicators__indicator__separator,.e-form__indicators--type-number .e-form__indicators__indicator__separator,.e-form__indicators--type-number_text .e-form__indicators__indicator__separator{margin-top:calc(var(--e-form-steps-indicator-padding, 30px) \/ 2 - var(--e-form-steps-divider-width, 1px) \/ 2)}.elementor-field-type-hidden{display:none}.elementor-field-type-html{display:inline-block}.elementor-field-type-tel input{direction:inherit}.elementor-login .elementor-lost-password,.elementor-login .elementor-remember-me{font-size:.85em}.elementor-field-type-recaptcha_v3 .elementor-field-label{display:none}.elementor-field-type-recaptcha_v3 .grecaptcha-badge{z-index:1}.elementor-button .elementor-form-spinner{order:3}.elementor-form .elementor-button>span{display:flex;justify-content:center;align-items:center}.elementor-form .elementor-button .elementor-button-text{white-space:normal;flex-grow:0}.elementor-form .elementor-button svg{height:auto}.elementor-form .elementor-button .e-font-icon-svg{height:1em}.elementor-select-wrapper .select-caret-down-wrapper{position:absolute;top:50%;transform:translateY(-50%);inset-inline-end:10px;pointer-events:none;font-size:11px}.elementor-select-wrapper .select-caret-down-wrapper svg{display:unset;width:1em;aspect-ratio:unset;fill:currentColor}.elementor-select-wrapper .select-caret-down-wrapper i{font-size:19px;line-height:2}.elementor-select-wrapper.remove-before:before{content:\"\"!important}<\/style>\t\t<form class=\"elementor-form\" method=\"post\" name=\"Captura de lead para baixar o material\">\n\t\t\t<input type=\"hidden\" name=\"post_id\" value=\"11230\"\/>\n\t\t\t<input type=\"hidden\" name=\"form_id\" value=\"3c22fad\"\/>\n\t\t\t<input type=\"hidden\" name=\"referer_title\" value=\"\" \/>\n\n\t\t\t\n\t\t\t<div class=\"elementor-form-fields-wrapper elementor-labels-\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-text elementor-field-group elementor-column elementor-field-group-name elementor-col-50 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-name\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tNome \t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"text\" name=\"form_fields[name]\" id=\"form-field-name\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"Nome\" required=\"required\" aria-required=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-type-email elementor-field-group elementor-column elementor-field-group-email elementor-col-50 elementor-field-required\">\n\t\t\t\t\t\t\t\t\t\t\t\t<label for=\"form-field-email\" class=\"elementor-field-label elementor-screen-only\">\n\t\t\t\t\t\t\t\tEmail\t\t\t\t\t\t\t<\/label>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<input size=\"1\" type=\"email\" name=\"form_fields[email]\" id=\"form-field-email\" class=\"elementor-field elementor-size-sm  elementor-field-textual\" placeholder=\"Email\" required=\"required\" aria-required=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<div class=\"elementor-field-group elementor-column elementor-field-type-submit elementor-col-100 e-form__buttons\">\n\t\t\t\t\t<button type=\"submit\" class=\"elementor-button elementor-size-sm\">\n\t\t\t\t\t\t<span >\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\" elementor-button-icon\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-button-text\">Download<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t<\/button>\n\t\t\t\t<\/div>\n\t\t\t<\/div>\n\t\t<\/form>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-17dc62f elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"17dc62f\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 126 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M10.7,6l2.5,2.6l-4,4.3l4,5.4l-2.5,1.9l-4.5-5.2l-3.9,4.2L0.7,17L4,13.1L0,8.6l2.3-1.3l3.9,3.9L10.7,6z M23.9,6.6l4.2,4.5L32,7.2l2.3,1.3l-4,4.5l3.2,3.9L32,19.1l-3.9-3.3l-4.5,4.3l-2.5-1.9l4.4-5.1l-4.2-3.9L23.9,6.6zM73.5,6L76,8.6l-4,4.3l4,5.4l-2.5,1.9l-4.5-5.2l-3.9,4.2L63.5,17l4.1-4.7L63.5,8l2.3-1.3l4.1,3.6L73.5,6z M94,6l2.5,2.6l-4,4.3l4,5.4L94,20.1l-3.9-5l-3.9,4.2L84,17l3.2-3.9L84,8.6l2.3-1.3l3.2,3.9L94,6z M106.9,6l4.5,5.1l3.9-3.9l2.3,1.3l-4,4.5l3.2,3.9l-1.6,2.1l-3.9-4.2l-4.5,5.2l-2.5-1.9l4-5.4l-4-4.3L106.9,6z M53.1,6l2.5,2.6l-4,4.3l4,4.6l-2.5,1.9l-4.5-4.5l-3.5,4.5L43.1,17l3.2-3.9l-4-4.5l2.3-1.3l3.9,3.9L53.1,6z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-223bc1e elementor-widget elementor-widget-text-editor\" data-id=\"223bc1e\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Entre em contato conosco para conhecer mais detalhes sobre todos os procedimentos empreendidos no processo de avalia\u00e7\u00e3o de risco de nitrosaminas, e dessa forma adiantar as demandas que a sua empresa possa ter!<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1642df5 elementor-widget elementor-widget-text-editor\" data-id=\"1642df5\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong>Uma empresa proativa est\u00e1 sempre preparada para os desafios da atualidade, se tornando uma refer\u00eancia de excel\u00eancia no mercado da sa\u00fade.<\/strong><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-68583c9 elementor-widget-divider--separator-type-pattern elementor-widget-divider--no-spacing elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"68583c9\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"divider.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-divider\" style=\"--divider-pattern-url: url(&quot;data:image\/svg+xml,%3Csvg xmlns=&#039;http:\/\/www.w3.org\/2000\/svg&#039; preserveAspectRatio=&#039;xMidYMid meet&#039; overflow=&#039;visible&#039; height=&#039;100%&#039; viewBox=&#039;0 0 126 26&#039; fill=&#039;black&#039; stroke=&#039;none&#039;%3E%3Cpath d=&#039;M10.7,6l2.5,2.6l-4,4.3l4,5.4l-2.5,1.9l-4.5-5.2l-3.9,4.2L0.7,17L4,13.1L0,8.6l2.3-1.3l3.9,3.9L10.7,6z M23.9,6.6l4.2,4.5L32,7.2l2.3,1.3l-4,4.5l3.2,3.9L32,19.1l-3.9-3.3l-4.5,4.3l-2.5-1.9l4.4-5.1l-4.2-3.9L23.9,6.6zM73.5,6L76,8.6l-4,4.3l4,5.4l-2.5,1.9l-4.5-5.2l-3.9,4.2L63.5,17l4.1-4.7L63.5,8l2.3-1.3l4.1,3.6L73.5,6z M94,6l2.5,2.6l-4,4.3l4,5.4L94,20.1l-3.9-5l-3.9,4.2L84,17l3.2-3.9L84,8.6l2.3-1.3l3.2,3.9L94,6z M106.9,6l4.5,5.1l3.9-3.9l2.3,1.3l-4,4.5l3.2,3.9l-1.6,2.1l-3.9-4.2l-4.5,5.2l-2.5-1.9l4-5.4l-4-4.3L106.9,6z M53.1,6l2.5,2.6l-4,4.3l4,4.6l-2.5,1.9l-4.5-4.5l-3.5,4.5L43.1,17l3.2-3.9l-4-4.5l2.3-1.3l3.9,3.9L53.1,6z&#039;\/%3E%3C\/svg%3E&quot;);\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-b5705e8 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b5705e8\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-43a55a3\" data-id=\"43a55a3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8b8faee elementor-headline--style-highlight elementor-widget elementor-widget-animated-headline\" data-id=\"8b8faee\" data-element_type=\"widget\" data-settings=\"{&quot;marker&quot;:&quot;double_underline&quot;,&quot;highlighted_text&quot;:&quot;InsilicAll&quot;,&quot;headline_style&quot;:&quot;highlight&quot;,&quot;loop&quot;:&quot;yes&quot;,&quot;highlight_animation_duration&quot;:1200,&quot;highlight_iteration_delay&quot;:8000,&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"animated-headline.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/insilicall.com\/wp-content\/plugins\/elementor-pro\/assets\/css\/widget-animated-headline.min.css\">\t\t<h3 class=\"elementor-headline\">\n\t\t\t\t\t<span class=\"elementor-headline-plain-text elementor-headline-text-wrapper\">Sobre a<\/span>\n\t\t\t\t<span class=\"elementor-headline-dynamic-wrapper elementor-headline-text-wrapper\">\n\t\t\t\t\t<span class=\"elementor-headline-dynamic-text elementor-headline-text-active\">InsilicAll<\/span>\n\t\t\t\t<\/span>\n\t\t\t\t<\/h3>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-cf5ea4f elementor-widget elementor-widget-text-editor\" data-id=\"cf5ea4f\" data-element_type=\"widget\" data-settings=\"{&quot;ultimate_floating_fx_translate_y&quot;:{&quot;unit&quot;:&quot;px&quot;,&quot;size&quot;:&quot;&quot;,&quot;sizes&quot;:[]}}\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-weight: 400\">Somos a primeira empresa LATAM que empodera a ind\u00fastria farmac\u00eautica em seus desafios de drug discovery e em toxicologia regulat\u00f3ria aplicando IA e automa\u00e7\u00e3o biol\u00f3gica. Com nosso modelo SaaS aumentamos a taxa de sucesso de nossos clientes levando medicamentos inovadores para os pacientes de forma mais r\u00e1pida e garantindo a seguran\u00e7a toxicol\u00f3gica de sua produ\u00e7\u00e3o. Nossa miss\u00e3o de entregar a melhor tecnologia com o menor impacto (ESG) nos permite garantir para nossos clientes a otimiza\u00e7\u00e3o de tempo, custos e experimenta\u00e7\u00e3o animal em seus processos.<\/span><\/p><p><span style=\"font-weight: 400\">Trabalhamos para aumentar a taxa de sucesso em levar medicamentos inovadores para as necessidades dos pacientes, diminuindo o cronograma, os custos e o tempo para que um novo produto chegue \u00e0 sociedade. Para isso, nossa empresa integra IA, computa\u00e7\u00e3o e automa\u00e7\u00e3o biol\u00f3gica para acelerar o design de novas mol\u00e9culas e prote\u00ednas terap\u00eauticas.<\/span><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Atualiza\u00e7\u00e3o da ANVISA sobre o controle de nitrosaminas em medicamentos de uso humano No dia 27 de Abril de 2022, [&hellip;]<\/p>\n","protected":false},"author":6,"featured_media":11240,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"rank_math_lock_modified_date":false,"footnotes":""},"categories":[110,79],"tags":[78,164,205,206,124,112,204,158,140],"class_list":["post-11230","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-atualidades","category-noticias","tag-anvisa","tag-medicamento","tag-medicamentos","tag-medicamentos-de-uso-humano","tag-nitrosamina","tag-nitrosaminas","tag-norma","tag-normativa","tag-rdc","no-social-count","single-post-item mb40"],"_links":{"self":[{"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/posts\/11230"}],"collection":[{"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/users\/6"}],"replies":[{"embeddable":true,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/comments?post=11230"}],"version-history":[{"count":92,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/posts\/11230\/revisions"}],"predecessor-version":[{"id":15240,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/posts\/11230\/revisions\/15240"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/media\/11240"}],"wp:attachment":[{"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/media?parent=11230"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/categories?post=11230"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/insilicall.com\/wp-json\/wp\/v2\/tags?post=11230"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}